Thursday, February 14, 2008

More Mercury Madness

J Child Neurol. 2007 Nov;22(11):1308-11.

Blood levels of mercury are related to diagnosis of autism: a reanalysis of an important data set.

Department of Psychology, University of Northern Iowa, Cedar Falls, Iowa 50614, USA. cathy.desoto@uni.edu

The question of what is leading to the apparent increase in autism is of great importance. Like the link between aspirin and heart attack, even a small effect can have major health implications. If there is any link between autism and mercury, it is absolutely crucial that the first reports of the question are not falsely stating that no link occurs. We have reanalyzed the data set originally reported by Ip et al. in 2004 and have found that the original p value was in error and that a significant relation does exist between the blood levels of mercury and diagnosis of an autism spectrum disorder. Moreover, the hair sample analysis results offer some support for the idea that persons with autism may be less efficient and more variable at eliminating mercury from the blood.

PMID: 18006963 [PubMed - in process]

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http://www.scipub.org/fulltext/ajbb/ajbb4273-84.pdf
Oxidative Stress in Autism: Elevated Cerebellar 3-nitrotyrosine Levels

American Journal of Biochemistry and Biotechnology 4 (2): 73-84, 2008
ISSN 1553-3468
© 2008 Science Publications
Corresponding Author: Elizabeth M. Sajdel-Sulkowska, D.Sc., Harvard Medical School/Brigham and Women’s Hospital,
Department of Psychiatry, BLI-151, 221 Longwood Ave., Boston, MA 02115, USA
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http://www.ncbi.nlm.nih.gov/pubmed/
A comparative evaluation of the effects of MMR immunization and mercury doses from thimerosal-containing childhood vaccines on the population prevalence of autism.

Mercury and autism: accelerating evidence?

Mercury in babies first haircuts

Baby teeth
are a good measure of cumulative exposure to toxic metals during fetal development and early infancy, so this study suggests that children with autism had a higher body burden of mercury during fetal/infant development. Antibiotic use is known to almost completely inhibit excretion of mercury in rats due to alteration of gut flora. Thus, higher use of oral antibiotics in the children with autism may have reduced their ability to excrete mercury, and hence may partially explain the higher level in baby teeth. Higher usage of oral antibiotics in infancy may also partially explain the high incidence of chronic gastrointestinal problems in individuals with autism.

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