one of the greatest cases in history of a drug disaster tragedy being caused by animal research.
First of all, Thalidomide had been tested on animals extensively prior to its marketing.
Even now, despite the clinical evidence to the contrary, British health authorities like the Medical Research Council maintain that the vast bulk of evidence from laboratory and animal tests is against thalidomide having any genetic effects.
The tragedy caused by Thalidomide in the 1960s was due to its teratogenic effects, ie effects on the foetus. Teratological effects of drugs were little known then. They were brought to public attention because of the Thalidomide tragedy on humans, therefore only after it. How on earth could animal researchers have thought of those effects before the disaster?
Even after the Thalidomide caused birth deformities in humans, researchers tried to reproduce the same effect in dozens of species of lab animals without success.
Friday, November 20, 2009
Fantastic Thalidomide Blog entry
Posted by S F X at 10:31 AM